This resource from JAMA Pediatrics, examines the clinical actionability of genetic findings in individuals with cerebral palsy.

It found that around 27% of tested individuals had identifiable genetic variants, with approximately 8% having findings that could directly influence clinical management. These results suggest that genetic sequencing may support precision medicine approaches in CP by informing diagnosis, guiding treatment decisions, and identifying targeted interventions, although further research is needed to strengthen the evidence base.

Genetic factors are increasingly recognised as contributing to a proportion of cerebral palsy cases, raising the possibility of more personalised approaches to care.