Randomized comparison trial of rehabilitation very early for infants with congenital hemiplegia

07 Jul 2025
5 minute read
The Journal of Paediatrics
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This resource from The Journal of Pediatrics examines Baby-CIMT vs. Baby-BIM in infants at risk of unilateral CP.

Hemiplegia affects around 50% of children with cerebral palsy (CP), the most common childhood physical disability. Two upper-limb (UL) therapies—bimanual therapy (BIM) and modified constraint-induced movement therapy (mCIMT)—have strong evidence of efficacy in school-aged children. BIM improves use of the affected hand in daily tasks, while mCIMT encourages use of the hemiplegic arm by constraining the stronger hand. Our meta-analysis showed both approaches are more effective than usual care, with similar outcomes when delivered in equal doses. However, they have not been compared in infants under 6 months with asymmetric brain lesions.

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